You can do that. There are 15 sensing pads on each axis. If you cut out one pad completely, you will have fewer pads (which means reduced sensing range on that axis, without an increase in resolution), if you cut out a corner you may find out that at different points of one axis you have different ranges on the other axis, for instance that at minimum x you can activate 10 pads on the y axis, while at maximum x you can activate 12 pads on the y axis.
Depending on the size and shape of your final shape is, you may want to use a Trill Hex as a starting point instead, as that has a finer resolution on each axis.
See the datasheet for specs on size and shapes: https://github.com/BelaPlatform/Trill/raw/master/trill_datasheet.pdf